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Exploring the Potential of Ozempic and Semaglutide in Revolutioning Alcohol Use Disorder Treatment, Clinical Trials, and Emerging Perspectives

Reading Time: 2 minutesIncreasing evidence suggests that drugs like Semaglutide, commonly known as Ozempic or Wegovy, could play a role in reducing alcohol cravings. Originally developed to address metabolic issues. These medications are now being scrutinized for their unexpected impact on the desire for alcohol. The potential connection between Ozempic and alcohol moderation introduces a compelling angle in pharmaceutical research. Offering new possibilities for addressing alcohol-related concerns and shedding light on the broader impacts of these medications. The utility of Ozempic and Wegovy extends beyond weight loss. The research spanning over a decade reveals unexpected side effects in drugs commonly employed to treat diabetes. They significantly reduce the desire for alcohol, often to a remarkable extent. The observed efficacy of drugs such as Semaglutide doesn’t come as a shock to physicians who have been prescribing this medication to their patients. As early as 2011, a study conducted in India highlighted the impact of liraglutide, a GLP-1 receptor utilized in diabetes treatment substantially decreasing alcohol consumption within a limited participant pool. Notably, nine out of 63 surveyed individuals had even abstained from alcohol entirely. This evidence suggests a consistent trend in the potential of this medication to influence alcohol intake positively. Indication of the potential use of these medications in alcoholism treatment dates back even further. The introduction of the first GLP-1 receptor agonist, exenatide occurred in 2005. Since then, anecdotal reports have consistently highlighted a diminishing desire for alcohol in individuals using such drugs. The prospect of an already-approved and safe drug curbing alcohol cravings raises tantalizing possibilities for its potential in treating Alcohol Use Disorder (AUD). A condition estimated to affect over 280 million globally. READ ASLO: Tech Worms: Unveiling Advancements and Hurdles In Artificial Biomimicry Subsequent research progress unfolded at gradual pace. Initially, investigators conducted animal experiments to assess the application of GLP-1 receptor agonists for decreasing alcohol consumption, demonstrating promising outcomes. In 2017, a Danish clinical trial led by Kruse Klausen investigated exenatide for treating Alcohol Use Disorder (AUD). While it showed no reduction in heavy-drinking days. Further analysis reveals efficiency, especially in obese participants. The trial’s limitations, including cognitive behavioral therapy and high dropout rates, prompted the exploration of Ozempic (semaglutide). Ozempic’s relative potency potentially offers broader benefits such as reducing cravings for food, smoking, and alcohol.

A Comprehensive Review of the OnePlus Open Foldable Smartphone

Kenyegon2 years ago2 years ago03 mins

Reading Time: 2 minutesDive into the future of smartphones with the OnePlus Open Foldable. This groundbreaking device redefines flexibility and resilience in the world of mobile technology. In this review, we explore its innovative features, rigorous durability test, and overall user experience. This positions it as a standout in the foldable smartphone arena. Join us on a brief journey into the unfolding possibilities of the OnePlus Open. Zack from the YouTube channel JerryRigEverything recently subjected the OnePlus Open. OnePlus inaugural foldable smartphone, to his customary durability test. As expected, the cover display features a glass surface that, like all glass material, exhibits scratches at level 6 on the Mohs hardness scale, with more pronounced grooves at level 7. The internal screen, typical of other foldable displays, is protected by a plastic layer that shows scratches at level 2 and deeper grooves at level 3. The phone’s edges are verified to be crafted from aluminum, and it appears to possess a reasonable level of dust resistance. The external display endures approximately 25 seconds when exposed to an open flame before the pixel transitions to a white hue, a typical response for OLED screens. In contrast, the plastic screen protector on the inner panel succumbs to burning in about five seconds. READ ALSO: The Best Gadgets and Technologies in 2023 In the conclusive bend test, the phone proves resilient to bending from either direction when in a folded state. Impressively, it withstands bending even in the opposite direction when in an open configuration. Although it doesn’t fully revert to its original shape after such strain. It maintains 100% functionality. OnePlus has faced challenges in the previous bend tests. Making it particularly gratifying to witness the resilience of what many might perceive as its most susceptible device to such assessments. This outcome serves as a reminder that reality can often defy expectations and bring surprises.

Jakadalla The Ohangla Star Celebrates 10 Years in Music Industry

Kenyegon2 years ago2 years ago03 mins

Reading Time: 2 minutesOver the weekend, the renowned Ohangla sensation Musa Jakadalla captivated a packed audience in a spectacular sold-out performance. The Greenspan Mall Grounds were filled with Ohangla enthusiasts and people from diverse backgrounds. Coming together for an evening of music and celebration. Musa Jakadala, born Moses Odhiambo Obok in 1989. He is a Kenyan singer and dancer hailing from Ugenya Ugunja. His music, marked by the hit “Hera Remo,” has gained widespread popularity on social media platforms like Boomplay. Starting in 2010 with Blaxe African Band, he ventured solo in 2013 after the success of “Nyar Alego.” He formed his own group and overcame early challenges to become a dominant figure in the Ohangla music scene. Jakadala’s universal appeal lies in his Dholuo-infused vibes and captivating beats, making his music accessible beyond language. The occasion marked Jakadalla’s impressive decade-long journey in the music industry. Drawing the presence of fellow artists, collaborators, and peers who gathered to honor the celebrated music icon on a special night. In a joyous moment, Jakadalla seized the opportunity to introduce his latest 9-track extended play (EP) titled “Kadallas Experience EP.” Entered the music scene with the explosive debut hit “Nyar Alego” in 2013. Jakadalla showcased his skill, prowess, and musical brilliance. Fans were treated to a lively experience as they danced to some of his other major hits, Including “Hera Remo,” “Asayi,” and ” Helena Mama.” A standout track from his latest EP is “Nde tu Nde,” a reimagining of a well-known Nyanza nursery rhyme. Skillfully modernized and adapted to resonate with contemporary audiences. READ ALSO: The Job Hunting Admist Graduate Influx: Stand Out to be the best Attended by a multitude of Jakadalla’s devoted fans. The event also drew the presence of notable Benga singer Prince Indah, along with Emma Jalamo, Elly Toto, Roy Thunder, Elvis Kadori, and other luminaries. Demonstrating mastery as a singer-songwriter. Jakadalla’s latest EP is brimming with songs that explore various aspects of life, covering themes such as love, heartbreak, societal reflections, enjoyment, and beyond.

King Charles’s Second Day of His Visit to Kenya

Kenyegon2 years ago2 years ago06 mins

Reading Time: 3 minutesOn Wednesday, King Charles III commences the second day of his Kenya visit. Acknowledging ” No excuse” for colonial-era abuses in East Africa under British rule. King Charles said he wished to “deepen my own understanding of these wrongs” during the four-day visit to Kenya with Queen Camilla. But also to bolster the ” modern partnership of equals facing today’s challenges.” Prior to his arrival, there were demands for King Charles to issue a formal apology to the nation. That endured decades of British colonial rule before Kenya’s hard-won independence in 1963. During his initial day in Kenya, the 74-year-old British monarch expressed that, the “Misdeeds of the past evoke the greetest sorrow and deepest regret.” Although he refrained from offering an apology. During a state banquet on Tuesday evening. King Charles articulated that there were deplorable and indefensible acts of violence committed against Kenyans in the midst of their strenuous quest for independence and sovereignty. He underscored that there can be no justification for these actions. He further added,” While we cannot alter the past, addressing our history with candor and transparency may serve as a testament to the strength of our current friendship, and hopefully, enable us to forge an even stronger bond in the years to come.” This marks King Charles’ first official visit to an African and Commonwealth nation since ascending to the throne last year. Despite having made three prior official visits to Kenya. In the upcoming days, during his stay in Nairobi and Mombasa, King Charles announced his intentions to pay his respects at the war graves’ cemetery. Honoring Africans who sacrificed their lives for Britain in the Second World War and also planting trees in memory of the late Kenyan conservationist Wangari Maathai. King Charles and Camilla received a formal red carpet reception on Tuesday from Kenya President Ruto. They subsequently placed a wreath at the Tomb of the Unknown Warrior located within the Uhuru Gardens Memorial Park. At this location, Kenya officially proclaimed its independence at the stroke of midnight on December 12, 1963. The Union flag was lowered, making way for the hoisting of the Kenyan Flag. However, the Uhuru Gardens Memorial Park also occupies the site where British colonial authorities had established a camp for detaining suspected Mau Mau guerrillas. During the brutal suppression of their 1952 to 1760 insurgency. It was referred to as the “Emergency” period. One of the most violent episodes in the history of the British Empire. Resulting in the death of at least 10,000 individuals primarily from the Kikuyu tribe. Tens of thousands more were rounded up and held without trial in camps, where accounts of executions, torture, and severe beatings were distressingly common. READ ALSO: Nairobi City Top List of Must-Visit Cities for 2024 Some advocacy groups had called on King Charles to issue a clear and public apology for these egregious abuses. President Dr. Ruto characterized the emergency period as a time that “amplified the most extreme aspects of colonial impunity”. He condemned the British response to Kenya’s struggle for self-determination as “Horridic in its brutality.” However, he expressed appreciation for the King, courage, and willingness to confront inconvenient realities. Kenya holds a significant place in history as it was where Queen Elizabeth II was. Then a princess received the news of her father King George VI’s passing in 1952. Marking the beginning of her remarkable 70-year reign. Charles emphasized Kenya’s enduring significance to his family. Highlighting his mother’s “special fondness” for the nation and its people. The royal agenda also places emphasis on addressing climate change and lending support to creative arts, technology, and the youth.

Nairobi City Top List of Must-Visit Cities for 2024

Kenyegon2 years ago2 years ago03 mins

Reading Time: 2 minutesIn a surprising turn of events, Nairobi capital city of Kenya, claims the title of the best city to visit in 2024. Outshining both Paris and Montreal. This vibrant East African metropolis has taken the travel world by storm with its rich cultural heritage, stunning landscapes, and a burgeoning arts scene that beckons adventures from around the globe. The Lonely Planet is a United States-based travel company. Has bestowed the honor of the top travel destination for 2024 upon Nairobi. Lonely Planet’s “Best in Travel 2024” list highlights ten travel destinations. Categorized into countries, cities, sustainability, and value. Nairobi- Capital city of Kenya secured the top position in the cities ranking, with Paris (France) and Montreal (Canada). Closely in second and third place respectively. The cities of Mostar in Bosnia and Philadelphia-USA rounded out the esteemed top five list. Placing sixth through tenth on the list, we find Manaus- Brazil, Jakarta-Indonesia, Prague- Czech Republic, Izamir-Turkey, and Kansas City in Missouri-USA in that order. Nairobi stood as the sole African city featured on the list. READ ALSO: The Most Economical Personal Cars in the World “Kenya’s capital is staking its claims as a global center of culture, sizzling with unmissable travel experiences. The city is shrugging off the colonial gaze and embracing its unique rhythms. with a dynamic array of restaurants, food carts, and cafes, along with a steady rotation of arts and cultural venues that all fuel a distinct Nairobi cool,” reads the Lonely Planet Website. Incorporate its namesake national park, abundant with wildlife and conveniently accessible from the city center, and you’ll create a truly unforgettable journey. Furthermore, according to Lonely Planet, Nairobi’s notable attraction encompasses watching traditional music and dance performances at the Bomas of Kenya. Embarking on a sunrise stroll through the Ngong Hills Forest for panoramic vistas of Mt. Kenya and Mt. Kilimanjaro. Exploring Nairobi National Park for an affordable safari set against the backdrop of the city’s changing skyline. Finally, they ascend to the pinnacle of the Kenyatta International Conference Center to enjoy a 360-degree view of the city.

The Most Economical Personal Cars in the World

Kenyegon2 years ago2 years ago03 mins

Reading Time: 2 minutesLooking for a new brand car that won’t drain your wallet on gas? Compact and subcompact models offer the best combination of affordability and high fuel economy to keep your costs down. The Toyota Corolla and Honda Civic are two of the most popular choices in this category. The legendary nameplates are praised for their reliability, longevity, and excellent real-world gas mileage of up to 40 mpg on the highway. Based models start around $20,000, but even higher trims deliver great value. Alternatively, you might consider the Hyundai Elantra, Kia Fote, Nissan Versa, and Chevrolet Sparks as excellent alternatives. These compact and subcompact vehicles deliver impressive highway fuel efficiency, with over 35 miles per gallon. While maintaining a starting price (MSRP) under $20,000 in most trim levels. They also provide a range of modern safety and technology features. All at a budget-friendly. To maximize your potential for saving, nothing quite compares to choosing a pre-owned vehicle. Deciding on a previously owned Toyota Prius hybrid or another highly efficient subcompact can yield gas mileage in the 40s or even higher. While you might have to forego some level of comfort, space, and features. Opting for a used economy car of this kind enables significant fuel savings to accumulate over the years of ownership. Irrespective of your financial constraints, you’ll discover both new and pre-owned models that strike a harmonious balance between the initial cost, ongoing expenses, and day-to-day practicality. When embarking on your search, direct your attention to compact, and subcompact categories in order to unearth the most cost-effective and efficient personal vehicles. READ ALSO:-The Best Gadgets and Technologies in 2023 It is also essential to conduct thorough research, obtain comprehensive information, and prioritize miles per gallon (MPG) above sheer power, size, and extra features. In conclusion, the most economical personal car can vary depending on your specific needs and priorities. When considering the economy of a car, you should take into account factors like purchase price, fuel efficiency, maintenance cost, and more importantly the resale value.

The Best Gadgets and Technologies in 2023

Kenyegon2 years ago2 years ago04 mins

Reading Time: 2 minutesKenya is embracing technology and experiencing positive advancement in the government. Embracing technology can lead to improved efficiency, accessibility, and transparency in government services and admirations, benefiting both citizens and the nation’s development. Here are some of the most exciting innovative gadgets and technologies that have emerged in 2023 so far: Foldable smartphone. Exemplified by models such as the Samsung Galaxy Fold and Motorola Razr, introduce flexible displays that seamlessly unfurl to offer an expanded screen size. These innovative devices represent a notable trend in the mobile phone industry. The consumer electronics market has witnessed the introduction of 8K TVS by leading manufacturers such as LG, Sony, and Samsung. These cutting-edge television sets deliver exceptionally high resolution, providing viewers with a truly immersive and enhancing viewing experience. The 5G connectivity. The evolution of cellular data networks of 5G connectivity was initially rolled out in numerous countries between 2019 and 2020. Offering significantly faster data speeds and reduced latency when compared to 4G LTE networks. In 2023, there has been a notable increase in the availability of devices compatible with %G technology. AI-powered smart assistants, including Amazon Alexa, Google Assistant, and Apple Siri. Continue to evolve becoming increasingly intelligent. These virtual assistants now have an improved ability to comprehend more natural language requests and execute more intricate tasks. Enhancing their utility and convenience for users. Wireless earbuds with features like active noise cancellation and touch controls. Exemplified by-products such as the AirPods Pro and Samsung Galaxy Buds Pro. Witnessed remarkable popularity. These advanced audio accessories offer users a convenient and immersive listening experience. Smart home device. Encompassing items such as intelligent speakers, security cameras, video doorbells, thermostats, and lighting systems, persist in their proliferation. These interconnected gadgets enable users to manage various aspects of their home environment via smartphone apps. READ ALSO: Green Prince Son of The Sheik Hassan Yousef Enhanced virtual and augmented reality headsets. Items like the Oculus Quest 2 are redefining the realm of immersive gaming and entertainment experiences. This cutting-edge device offers users a new level of interactivity and immersion in virtual worlds. The Electric-Vehicle. The electric vehicle market saw the introduction of more affordable EV models. Including the Ford Mustang March-E and Hyundai Ioniq 5. These vehicles offer longer driving ranges, making electric transportation more accessible and practical for a broader range of consumers. Moreso, companies persist in advancing fitness trackers like fitness bands and smartwatches. Designed to monitor various health metrics such as heart rate, sleep patterns, and more. This wearable device enables users to stay proactive in managing their health and fitness goals.

NTSA Calls on vehicle owners to Collect Their New Number Plates

Kenyegon2 years ago2 years ago03 mins

Reading Time: 2 minutesThe National Transport and Safety Authority (NTSA) is encouraging drivers who have received SMS notifications about the availability of the new generation number plate to promptly visit their designated centers. In a statement released on Wednesday. NTSA emphasized that drivers should personally visit the specific centers they had identified during the application process. To expedite the issuance of the new generation number plates. The NTSA extended its operating hours, shifting from the previous 8 a.m. to 5 p.m. Schedule to operate from 7:30 a.m. to 6 p.m. on weekdays. Roads and Transport Cabinet Secretary Kipchumba Murkomen directed the authority to address the blocking in printing Driving licenses, logbooks, and digital number plates within a two-week timeframe. Promoting this adjustment in operating hours. READ ALSO: Green Prince Son of The Sheik Hassan Yousef In May 2022, under the guidance of Fred Matiangi, former interior Cabinet Secretary. The new generation vehicle registration plates were introduced as part of efforts to combat forgery, swapping, and duplication. Main function of NTSA Below are the main functions of NTSA in Kenya;

Green Prince Son of The Sheik Hassan Yousef

Kenyegon2 years ago2 years ago04 mins

Reading Time: 2 minutesGreen Prince is a nickname for Mosab Hassan Yousef. A Palestinian who worked as an informant for the Israeli intelligence agency Shin Bet. Moasab Hassan is the son of Sheikh Hassan Yousef, the founding member of Hamas, a Palestinian political and military organization. Green Prince became a valuable asset for the Israeli intelligence agency by providing information on Hamas activities and preventing numerous terrorist attacks, His story is detailed in the book ” SON of HAMAS,” which he authored. The documentary film ” The Green Prince,” tells the story of his collaboration with Israeli intelligence. His action and decision to work with the Israeli government were controversial and led to significant personal and political consequences. The Green Prince has delivered several powerful speeches in the past. Particularly about his experiences and his perspective on the Israeli-Palestinian conflict. One notable speech was his testimony at the United Nations in 2017. In this speech, he talked about his personal journey, the need for peace and reconciliation, and the importance of understanding the human side of the conflict. READ ALSO: Israel-Palestine Conflict’s Active Influence on the World Fuel Price Below is an excerpt of his UN Speech; ” I am not here to tell you that I have the answer, that I hold the key to peace in the Middle East. I am here to tell you that it’s time to start thinking differently. It’s time to look at the bigger picture, at the human side of the conflict. We need to acknowledge each other’s pain, fear, and hopes. We need to see the humanity in one another. This conflict is not just about politics or borders. It’s about people, families, and children on both sides who deserve a better future. I have seen firsthand the suffering and the consequences of this conflict. I have seen the pain in the eyes of Israeli mothers who have lost their sons and daughters in suicide bombings. I have also seen the pain in the eyes of Palestinian mothers who have lost their children to the conflict. We are all victims of this ongoing tragedy, and it’s time for it to end. We must move beyond hatred and revenge. We must seek reconciliation and understanding. We must work together to build a brighter and more peaceful future for the generation to come. It won’t be easy, but it’s possible if we have the courage to take the first steps towards peace.” The speech reflects Mosab Hassan Yousef’s call for empathy, understanding, and reconciliation in the Israeli-Palestinian conflict.

Israel-Palestine Conflict’s Active Influence on the World Fuel Price

Kenyegon2 years ago2 years ago04 mins

Reading Time: 2 minutesThe Israel-Palestine Conflict actively impacts fuel prices. Drawing global attention due to its potential to disrupt oil supply chains. This conflict, situated in the Middle East, a region rich in oil reserves and a vital energy hub can cause fluctuation in fuel prices on a global scale. The conflict’s influence on fuel prices underscores the intricate web of geopolitics, economics, and energy security that characterizes our interconnected world. As events continue to unfold, experts and policymakers closely monitor how these ongoing conflicts may actively send ripples throughout the global energy market. Tetu Member of Parliament Geoffrey Wandeto. Has stirred anxiety by highlighting the potential impact of the Israel-Palestine conflict on fuel prices. He emphasized the ongoing conflict between Israel and the Palestinian Islamist militant group Hamas. This could lead to additional surges in oil prices. Also, he voiced specific concerns, noting that fuel prices in Kenya have already experienced a surge. READ ALSO: While appearing on the Citizen TV show Wandeto clarified the conflict’s outcomes in the coming weeks. May exert substantial pressure on global oil production. He stressed that an extended Israel-Hamas conflict might push oil prices beyond Keny’s comfortable threshold. “We cannot downplay the new conflict between Israel and Palestine that has a significant impact on fuel prices,” he said. Furthermore, Wandeto proposed that boosting exports could ease Kenya’s dollar shortage. Which has been impacting the country due to various factors, including a decline in exports. He put forth the idea of actively exploring alternative settlement currencies for global trade. Also, the idea of promoting trading within East Africa using local currencies is a potential solution. “This whole dollar thing thing is not just a Kenya thing. I read that Japan, which has a very strong economy, has less than 20 percent or so devaluation of their currency. Almost all countries in the world are hurting because what is happening in America is that they are trying to cool their economy from inflation,” he said. He added, ” Now we are all victims of whatever goes on in America. When America coughs, the whole world catches a cold.” Wandeto also highlighted the increasing global demand for oil products, driven by the resurgence of the Chinese economy. The combination of this demand and concerns that the Israel-Hamas conflict could expand into the petroleum-producing Gulf region has resulted in rising oil prices.